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Tadalafil (Cialis) is one of the most popular erectile dysfunction (ED) drugs. Its major appeal? The drug comes in low-dose versions that can be taken daily. This means you can have sex at any time, rather than needing to take a pill from time to time as needed like other ED brands. The starting dose for daily-use Cialis is 2.5 milligrams (mg). Tadalafil is a reversible phosphodiesterase type 5 (PDE5) inhibitor approved for the treatment of erectile dysfunction (ED). As a class, PDE5 inhibitors (including sildenafil cialis usage for ed By controlling the enzyme, tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection. What are the recommended doses of Cialis (tadalafil) for the treatment of erectile dysfunction and benign prostatic hyperplasia? Cialis (tadalafil) is available for use as needed or for use once daily. Regardless of therapy schedule, tadalafil should not be taken more than once per day. CIALIS for Once Daily Use for Erectile Dysfunction and Benign Prostatic Hyperplasia. The recommended dose of CIALIS for once daily use is 5 mg, taken at